Need to outsource data management or analysis projects for your safety programs?
GeneGo’s expert toxicology and chemistry staff can help.
We offer flexible and affordable customized services to support safety assessment at multiple levels.
Data Analysis Services
- Rapid-turnaround safety analysis reports from gene/protein lists or microarray data
- Matches to safety-related categories
- Toxicity biomarkers and processes
- Xenobiotic metabolism effects
- Pathways and biological processes
- Statistically-significant networks
- Custom in-depth systems toxicology data analysis reports
- Integrated analysis or comparison of multiple data types
- Mechanisms of toxicity
- Compound comparisons
- Safety and efficacy biomarkers
- Evaluation of target linkage to safety findings
- Differentiation of on- and off-target effects
- Chemical structure predictive analysis reports
- Metabolism and reactive metabolites
- QSAR modeling of ADME-Tox properties and therapeutic potential
- Target prediction and biological evaluation of potential pharmacological effects
- Pathway Maps
- Toxicity networks
- Biological processes
Knowledge Management Services
- Development of standardized nomenclatures and ontologies
- Safety assays
- Preclinical safety findings
- Clinical adverse drug reactions
- Curation and annotation services (on or off-site)
- Curation and collation of historical safety data from preclinical studies
- Curation and collation of safety data from clinical trials
- Curation and collation of postmarketing safety data
Expert Knowledge Generation Services
- Target assessment reports
- Custom Pathway Maps
- Mechanisms of toxicity
- Compound mode of action
- Target interactions with pathways related to particular biological processes or in various tissues
- Interactions of xenobiotics with critical pathways
- Competitive intelligence reports on safety issues
- Development of custom predictive QSAR models for ADME-Tox endpoints
- Organ toxicity
- Mutagenicity/carcinogenicity
- Safety pharmacology
Contact us today to for more details or to discuss your particular needs with one of our scientists. We will customize a program to help you achieve your goals.
genegosales@thomsonreuters.com, Tel: 760-230-0169
“We outsourced prioritization of three compounds to GeneGo. While we understood the effect of these drugs, we needed to prioritize them with respect to biologic potency and possible toxicity. GeneGo's software was able to confirm the biologic activity that we expected and highlighted functional processes and key drug targets that allowed us to focus our testing by suggesting biological activities that could be critical to the success of the candidates, saving us time and money.”