Toxicology
Please click on the toxicology references below to read the entire article. Check back occasionally as new toxicology articles will be posted.
2008
2007
- Dose response evaluation of gene expression profiles in the skin of K6/ODC mice exposed to sodium arsenite
( Toxicology and Applied Pharmacology Volume 227, Issue 3, 15 March 2008, Pages 400-416 )
- Transcriptional responses in thyroid tissues from rats treated with a tumorigenic and a non-tumorigenic triazole conazole fungicide
( Toxicology and Applied Pharmacology Volume 227, Issue 3, 15 March 2008, Pages 357-369 )
- Affymetrix and Illumina, a toxicogenomic based interplatform interplatform comparison
( Molecular Toxicology, Institute of Toxicology, Merck Serono Research, 64271 Darmstadt, Germany )
- Acute Hepatotoxicity: A Predictive Model Based on Focused Illumina Microarrays
( Toxicological Sciences 99(1), 289-302 (2007) )
- Overlapping gene expression profiles of model compounds provide opportunities for immunotoxicity screening.
( Toxicol. Appl. Pharmacol. (2007), doi:10.1016/j.taap.2007.08.026 )
- Toxicogenomics in the assessment of immunotoxicity
( Methods 41, 132-141, 2007 )
- In vitro immunotoxicity of bis(tri-n-butyltin)oxide (TBTO) studied by toxicogenomics
( Toxicology 2007, accepted )
- Estrogenic Effects in the Immature Rat Uterus after Dietary Exposure to Ethinylestradiol and Zearalenone Using a Systems Biology Approach
( Toxicological Sciences 99(1), 303-314 (2007) )
2006
2005
- Systems level analysis of drug metabolism and its effects in human biology
( Bioinformatics. 2005, submitted )
- A Combined Approach to Drug Metabolism and Toxicity Assessment
( Drug Metabolism and Disposition 34:495-503, 2006 )
- Reengineering the pharmaceutical industry by crash-testing molecules
( Drug Disc Today, Vol.10 Num. 17, September 2005 )
- Computational prediction of Human Drug Metabolism
( xpert Opinion. Drug Metab. Toxicol. (2005) )
- Use of the local lymph node assay in assessment of immune function
( Toxicology 211, 107-114, 2005 )
- A Novel Method for Generation of Signature Networks as Biomarkers from Complex High Throughput Data
( Tox. Letters 158: 20-29, 2005 )
- Application of systems biology to absorption, distribution, metabolism, excretion and toxicity
( Trends in Pharmacological Sciences, Vol.26, No.4, 202-209, April 2005 )
- A Novel Method for Visualizing Nuclear Hormone Receptor Networks Relevant to Drug Metabolism
( Drug Metabolism and Disposition, Vol.33, No.3 2005 )
2004
2003
Mary E. Edgerton, a pathologist performing cancer research at MD Anderson and a long-term client, says “I have been using Metacore for many years in my research into pathways and networks that control aggressive behavior in cancers. I am currently using it to infer networks from analysis of gene expression array data for pathways in lung, brain, and breast cancer. I also use the curated pathways to formulate mathematical models of molecular networks that predict tumor behavior using multiscale modeling. Not only do I find the product to be very useful, but I also appreciate the responsiveness of the staff at Genego to my technical questions and suggestions.”