- Your trusted guide in any data range!
- A user-friendly wizard that will manage, annotate, and statistically process your data in minutes!

WHY DataRanger?

• Still managing your data columns in Excel?
• Need an easy way to tether metadata to your experiments?
• Want to process and annotate files without having to be a stats expert or learning complicated software?

Use DataRanger for:

• Managing gene expression data and corresponding metadata
• Annotation and organization of expression data files
• Raw microarray data processing and statistical workup
• Regulatory/Signalling Pathway Analysis of microarray data
• Sample grouping and comparisons
• Functional Analysis of Clinical Data

Who Can Benefit:

• Systems Biology researchers dealing with microarray data analyses in commercial and academic settings
• Drug discovery and diagnostics groups that deal with drug-related expression signatures
• Disease Biomarker groups to elucidate key disease mechanisms and propose better biomarkers and treatment targets
• Bioinformatics departments that need a standardized way of data processing, annotation, and shared research solutions

DataRanger Highlights

From what the data “is” to what the data “means,” DataRanger can quickly take you through any data forest and deliver valuable knowledge:

• Start with raw or processed data (Excel, .txt, .csv, .CEL format) or a .soft file from GEO
• Breeze through annotation and file organization steps with our controlled vocabulary terms or add your own
• Normalize and statistically process the data with RMA, FDR, filtering, DEG, and GSEA using GeneGo functional ontologies
• Get your data with all the analysis settings and metadata factors saved in the Data Manager and stored within experiment properties
• OR launch a MetaCore analysis workflow immediately at the last step with a comprehensive report summary

PRODUCT OVERVIEW

DataRanger™ is a part of GeneGo’s integrated software suite for functional analysis of Omics data. DataRanger is designed for anyone to quickly obtain the most significant and valuable components of the data, organize and statistically process the files, and use filters, workflows or enrichments that are based on the standard vocabulary and ontology from GeneGo’s underlying proprietary manually curated database. The wizard allows fast and easy processing and includes intuitive tools for data visualization, analysis, and enrichments, filters, and easy to use workflows. Moreover, user metadata and analysis settings get captured and stored along with each sample’s properties upon the completion of the wizard. This provides a unique and standardized solution for anyone dealing with functional or pathway analysis of microarray data.

PARSER

Auto-recognition and semi-automated processing of Excel, .txt, .csv, or .CEL format or .soft files from GEO

STATISTICAL FILTERS

• Variable threshold filtering
• Filter by selecting top 300 or top “n” genes from each data sample
• FDR threshold filtering

FUNCTIONAL FILTERS

• GO processes
• Disease
• Tissue
• Sub cellular localization
• Interaction types
• Object types
• Metabolites
• Body fluids
• Species/orthologs (human, mouse, rat, dog, chicken, worm, chimpanzee, bovine, zebrafish, fly, mosquito, mold, bread mold, baker.s yeast, fission yeast, arabidopsis, rice, candida)

ONTOLOGIES THAT CAN BE USED FOR GSEA

• Canonical Pathway Maps
• GeneGo Process Networks
• GeneGo Metabolic Networks
• GeneGo Disease Networks
• GeneGo Drug Target Networks
• GeneGo Toxicity Networks
• GeneGo Diseases
• GO Processes
• GO Localization
• GO Molecular Function

AUTOMATED WORKFLOWS WITH REPORTS

The last step of the wizard provides an option to launch a universal analysis workflow, which would provide functional analysis of the data with enrichments and ranking, as well as custom network building that captures the top interconnected modules for the dataset

CONTENT

DataRanger uses ontologies from MetaBase, which is a manually curated proprietary database built by GeneGo PhD and M.D. employees reading full text articles that cover 2700 journals and dating back to the 60’s.

Contact us at 858-756-7996 to find out more about DataRanger

For a sample FREE WALK-THROUGH, please visit GeneGo at Molecular Medicine Tri-Conference in San Francisco Feb 23-25, 2011 where we will be highlighting DataRanger! Bring your data in excel, txt, or .soft formats to booth #403, and we will analyze it for you on the spot!

Join our next DataRanger Webinar on Friday, Feb 18th 2011 at 9am PST/12pm EST.

To receive webinar invitations please email training@genego.com.